For many centuries earthworm has been used in the Far East traditional medical practice for maintaining circulatory health. It was recorded in the “Ben Cao Gang Mu”, the traditional Eastern world’s pharmacopoeia, as a potent medicine for “Liver Wind uprising” conditions.
In order to elucidate the power of earthworms, Japanese scholars Dr. Hisashi Mihara and others succeeded in extracting a fibrin-dissolving enzyme from Lumbricus rubellus in the 1980s. This enzyme was later found to consist of a few proteolytic sub-enzymes, which are collectively named lumbrokinase. Lumbrokinase is also referred to as earthworm fibrinolytic enzymes (EFE), earthworm powder enzymes (EPE), or e-PA.
Since then many Korean and Chinese researchers have compiled extensive scientific and clinical data on lumbrokinase extracted from Lumbricus rubellus and Eisenia fetida. In Japan and Korea lumbrokinase has been the main ingredient in “Dragon Heart”, a popular health supplement for supporting circulatory health. Whereas in China, earthworm protein extracts and lumbrokinase have been studied thoroughly and have been used to support a healthy circulation.
As science and technology advanced over the last century, so did the knowledge about the active constituents in traditional medicine.
First there was dried earthworms used in traditional oriental medicine decoctions, and then there was ground-up earthworm powder. Later came the granular crude extract of earthworms, and now there is Boluoke®, a nutraceutical product containing purified enzymes extracted from earthworms. Just like omega-3 molecules in fish oil, polyphenols in green tea, and curcumin and turmeric, the group of enzymes called lumbrokinase shall in time be known as the most valuable ingredients in earthworms
Boluoke® (lumbrokinase) is the only fully researched oral enzyme on the market supporting a healthy circulation in the body. For most people, Boluoke® can support the body in keeping the system in a more balanced state.
* The statements above have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.